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Abnormalities of granule cell dendritic structure are a prominent feature of the intrahippocampal kainic acid model of epilepsy despite reduced post-injury neurogenesis

PURPOSE: Aberrant plastic changes among adult-generated hippocampal dentate granule cells are hypothesized to contribute to the development of temporal lobe epilepsy. Changes include formation of basal dendrites projecting into the dentate hilus. Innervation of these processes by granule cell mossy...

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Detalhes bibliográficos
Main Authors: Murphy, Brian L., Hofacer, Rylon D., Faulkner, Christian N., Loepke, Andreas W., Danzer, Steve C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3340618/
https://ncbi.nlm.nih.gov/pubmed/22533643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1528-1167.2012.03463.x
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