Genome-wide association study of lung function decline in adults with and without asthma

BACKGROUND: Genome-wide association studies (GWAS) have identified determinants of chronic obstructive pulmonary disease, asthma and lung function level, however none addressed decline in lung function. AIM: We conducted the first GWAS on age-related decline in forced expiratory volume in the first...

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Auteurs principaux: Imboden, Medea, Bouzigon, Emmanuelle, Curjuric, Ivan, Ramasamy, Adaikalavan, Kumar, Ashish, Hancock, Dana B, Wilk, Jemma B, Vonk, Judith M, Thun, Gian A, Siroux, Valerie, Nadif, Rachel, Monier, Florent, Gonzalez, Juan R, Wjst, Matthias, Heinrich, Joachim, Loehr, Laura R, Franceschini, Nora, North, Kari E, Altmüller, Janine, Koppelman, Gerard H., Guerra, Stefano, Kronenberg, Florian, Lathrop, Mark, Moffatt, Miriam F, O’Connor, George T, Strachan, David P, Postma, Dirkje S, London, Stephanie J, Schindler, Christian, Kogevinas, Manolis, Kauffmann, Francine, Jarvis, Debbie L, Demenais, Florence, Probst-Hensch, Nicole M
Format: Artigo
Langue:Inglês
Publié: 2012
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3340499/
https://ncbi.nlm.nih.gov/pubmed/22424883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2012.01.074
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