The impact of drug metabolizing enzyme polymorphisms on outcomes after antenatal corticosteroid use

OBJECTIVE: To determine the impact of maternal and fetal single nucleotide polymorphisms (SNPs) in key betamethasone (BMZ) pathways on neonatal outcomes. STUDY DESIGN: DNA was obtained from women given BMZ and their infants. Samples were genotyped for 73 exploratory drug metabolism and glucocorticoi...

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Huvudupphovsmän: Haas, David M., Lehmann, Amalia S., Skaar, Todd, Philips, Santosh, McCormick, Catherine L., Beagle, Kyle, Hebbring, Scott J., Dantzer, Jessica, Li, Lang, Jung, Jeesun
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2012
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3340461/
https://ncbi.nlm.nih.gov/pubmed/22445700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajog.2012.02.016
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