Analytical characterization of ch14.18: A mouse-human chimeric disialoganglioside-specific therapeutic antibody

Ch14.18 is a mouse-human chimeric monoclonal antibody to the disialoganglioside (GD2) glycolipid. In the clinic, this antibody has been shown to be effective in the treatment of children with high-risk neuroblastoma, either alone or in combination therapy. Extensive product characterization is a pre...

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Main Authors: Soman, Gopalan, Kallarakal, Abraham T, Michiel, Dennis, Yang, Xiaoyi, Saptharishi, Nirmala, Jiang, Hengguang, Giardina, Steve, Gilly, John, Mitra, George
Format: Artigo
Sprog:Inglês
Udgivet: Landes Bioscience 2012
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Report
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3338943/
https://ncbi.nlm.nih.gov/pubmed/22327432
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