The Insulin Receptor Substrate 1 (Irs1) in Intestinal Epithelial Differentiation and in Colorectal Cancer

Colorectal cancer (CRC) is associated with lifestyle factors that affect insulin/IGF signaling, of which the insulin receptor substrate 1 (IRS1) is a key transducer. We investigated expression, localization and pathologic correlations of IRS1 in cancer-uninvolved colonic epithelium, primary CRCs wit...

Full description

Saved in:
Bibliographic Details
Main Authors: Esposito, Diana L., Aru, Federica, Lattanzio, Rossano, Morgano, Annalisa, Abbondanza, Michela, Malekzadeh, Reza, Bishehsari, Faraz, Valanzano, Rosa, Russo, Antonio, Piantelli, Mauro, Moschetta, Antonio, Lotti, Lavinia Vittoria, Mariani-Costantini, Renato
Format: Artigo
Language:Inglês
Published: Public Library of Science 2012
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3338610/
https://ncbi.nlm.nih.gov/pubmed/22558377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0036190
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items