Homocysteine, methylenetetrahydrofolate reductase C677T polymorphism and cognitive impairment: the health in men study

High total plasma homocysteine (tHcy) has been associated with cognitive impairment in later life, but it is unclear if this association is causal or is due to confounding. The C677T polymorphism of the 5,10 methylenetetrahydrofolate reductase gene (MTHFR) increases basal tHcy, but its contribution...

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Main Authors: Ford, A H, Flicker, L, Hankey, G J, Norman, P, van Bockxmeer, F M, Almeida, O P
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2012
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Original Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3335075/
https://ncbi.nlm.nih.gov/pubmed/21358708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mp.2011.18
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