Systemic Immunoregulatory and Proteogenomic Effects of Tacrolimus to Sirolimus Conversion in Liver Transplant Recipients

Immunosuppression withdrawal from calcineurin inhibitors is only possible in ~20% of liver transplant recipients. However, mTOR inhibitors (sirolimus) appear to be more immunoregulatory and might promote a tolerant state for withdrawal. Our purpose was to determine if systemic (blood, marrow, allogr...

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Detalhes bibliográficos
Main Authors: Levitsky, Josh, Mathew, James M., Abecassis, Michael, Tambur, Anat, Leventhal, Joseph, Chandrasekaran, Dhivya, Herrera, Nancy, Al-Saden, Patrice, Gallon, Lorenzo, Abdul-Nabi, Anmaar, Yang, Guang-Yu, Kurian, Sunil M., Salomon, Daniel R., Miller, Joshua
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3334454/
https://ncbi.nlm.nih.gov/pubmed/22234876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.25579
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