Toward a Molecular Understanding of Protein Solubility: Increased Negative Surface Charge Correlates with Increased Solubility

Protein solubility is a problem for many protein chemists, including structural biologists and developers of protein pharmaceuticals. Knowledge about how intrinsic factors influence solubility is limited due to the difficulty of obtaining quantitative solubility measurements. Solubility measurements...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Kramer, Ryan M., Shende, Varad R., Motl, Nicole, Pace, C. Nick, Scholtz, J. Martin
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The Biophysical Society 2012
Gaiak:
Protein
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3328702/
https://ncbi.nlm.nih.gov/pubmed/22768947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.01.060
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