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Toward a Molecular Understanding of Protein Solubility: Increased Negative Surface Charge Correlates with Increased Solubility

Protein solubility is a problem for many protein chemists, including structural biologists and developers of protein pharmaceuticals. Knowledge about how intrinsic factors influence solubility is limited due to the difficulty of obtaining quantitative solubility measurements. Solubility measurements...

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Detaylı Bibliyografya
Asıl Yazarlar: Kramer, Ryan M., Shende, Varad R., Motl, Nicole, Pace, C. Nick, Scholtz, J. Martin
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The Biophysical Society 2012
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3328702/
https://ncbi.nlm.nih.gov/pubmed/22768947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.01.060
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