Mitigating age-related immune dysfunction heightens the efficacy of tumor immunotherapy in aged mice

Although cancer tends to affect the elderly, most preclinical studies are performed in young subjects. In this study, we developed a melanoma-specific cancer immunotherapy that shows efficacy in aged but not young hosts by mitigating age-specific tumor-associated immune dysfunction. Both young and a...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Hurez, Vincent, Daniel, Benjamin J., Sun, Lishi, Liu, Ai-Jie, Ludwig, Sara M., Kious, Mark J., Thibodeaux, Suzanne R., Pandeswara, Srilakshmi, Murthy, Kruthi, Livi, Carolina B., Wall, Shawna, Brumlik, Michael J., Shin, Tahiro, Zhang, Bin, Curiel, Tyler J.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3328641/
https://ncbi.nlm.nih.gov/pubmed/22496463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-11-3019
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker