Circulating Factors Induce Coronary Endothelial Cell Activation Following Exposure to Inhaled Diesel Exhaust and Nitrogen Dioxide in Humans: Evidence From a Novel Translational In Vitro Model

The vascular toxicity of inhaled agents may be caused by soluble factors that are released into the systemic circulation. To confirm this in a straightforward manner, we obtained plasma from healthy human volunteers before and after exposure to diesel exhaust (DE) and nitrogen dioxide (NO(2)). Plasm...

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Bibliographic Details
Main Authors: Channell, Meghan M., Paffett, Michael L., Devlin, Robert B., Madden, Michael C., Campen, Matthew J.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2012
Subjects:
In Vitro Methods and Alternatives to Animals
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3327867/
https://ncbi.nlm.nih.gov/pubmed/22331494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfs084
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