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Peroxisome proliferator-activated receptor-alpha gene level differently affects lipid metabolism and inflammation in apolipoprotein E2 knock-in mice
OBJECTIVE: Peroxisome Proliferator-Activated Receptorα (PPARα) is a ligand-activated transcription factor which controls lipid metabolism and inflammation. PPARα is activated by fibrates, hypolipidemic drugs used in the treatment of dyslipidemia. Previous studies assessing the influence of PPARα ago...
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| Главные авторы: | , , , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Lippincott Williams & Wilkins
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3327645/ https://ncbi.nlm.nih.gov/pubmed/21474829 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.110.220525 |
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