Peroxisome proliferator-activated receptor-alpha gene level differently affects lipid metabolism and inflammation in apolipoprotein E2 knock-in mice

OBJECTIVE: Peroxisome Proliferator-Activated Receptorα (PPARα) is a ligand-activated transcription factor which controls lipid metabolism and inflammation. PPARα is activated by fibrates, hypolipidemic drugs used in the treatment of dyslipidemia. Previous studies assessing the influence of PPARα ago...

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Détails bibliographiques
Auteurs principaux: Lalloyer, Fanny, Wouters, Kristiaan, Baron, Morgane, Caron, Sandrine, Vallez, Emmanuelle, Vanhoutte, Jonathan, Baugé, Eric, Shiri-Sverdlov, Ronit, Marten, Hofker, Staels, Bart, Tailleux, Anne
Format: Artigo
Langue:Inglês
Publié: Lippincott Williams & Wilkins 2011
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3327645/
https://ncbi.nlm.nih.gov/pubmed/21474829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.110.220525
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