Genetic association study of NF-κB genes in UK Caucasian adult and juvenile onset idiopathic inflammatory myopathy

Objective. Treatment-resistant muscle wasting is an increasingly recognized problem in idiopathic inflammatory myopathy (IIM). TNF-α is thought to induce muscle catabolism via activation of nuclear factor-kappa B (NF-κB). Several genes share homology with the NF-κB family of proteins. This study inv...

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Bibliographic Details
Main Authors: Chinoy, Hector, Li, Charles K.-C., Platt, Hazel, Fertig, Noreen, Varsani, Hemlata, Gunawardena, Harsha, Betteridge, Zoe, Oddis, Chester V., McHugh, Neil J., Wedderburn, Lucy R., Ollier, William E. R., Cooper, Robert G.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2012
Subjects:
Basic Science
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3327167/
https://ncbi.nlm.nih.gov/pubmed/22210660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/rheumatology/ker379
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