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Structure and function of both domains of ArnA, a dual function decarboxylase and a formyltransferase, involved in 4-amino-4-deoxy-L-arabinose biosynthesis
Modification of the lipid A moiety of lipopolysaccharide by the addition of the sugar, 4-amino-4-deoxy-L-arabinose (L-Ara4N), is a strategy adopted by pathogenic Gram-negative bacteria to evade cationic antimicrobial peptides produced by the innate immune system. L-Ara4N biosynthesis is therefore a...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2005
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3326539/ https://ncbi.nlm.nih.gov/pubmed/15809294 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M501534200 |
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