Multistep Ion Channel Remodeling and Lethal Arrhythmia Precede Heart Failure in a Mouse Model of Inherited Dilated Cardiomyopathy

BACKGROUND: Patients with inherited dilated cardiomyopathy (DCM) frequently die with severe heart failure (HF) or die suddenly with arrhythmias, although these symptoms are not always observed at birth. It remains unclear how and when HF and arrhythmogenic changes develop in these DCM mutation carri...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Suzuki, Takeshi, Shioya, Takao, Murayama, Takashi, Sugihara, Masami, Odagiri, Fuminori, Nakazato, Yuji, Nishizawa, Hiroto, Chugun, Akihito, Sakurai, Takashi, Daida, Hiroyuki, Morimoto, Sachio, Kurebayashi, Nagomi
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Public Library of Science 2012
Θέματα:
Research Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3325934/
https://ncbi.nlm.nih.gov/pubmed/22514734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0035353
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