Multistep Ion Channel Remodeling and Lethal Arrhythmia Precede Heart Failure in a Mouse Model of Inherited Dilated Cardiomyopathy

BACKGROUND: Patients with inherited dilated cardiomyopathy (DCM) frequently die with severe heart failure (HF) or die suddenly with arrhythmias, although these symptoms are not always observed at birth. It remains unclear how and when HF and arrhythmogenic changes develop in these DCM mutation carri...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Suzuki, Takeshi, Shioya, Takao, Murayama, Takashi, Sugihara, Masami, Odagiri, Fuminori, Nakazato, Yuji, Nishizawa, Hiroto, Chugun, Akihito, Sakurai, Takashi, Daida, Hiroyuki, Morimoto, Sachio, Kurebayashi, Nagomi
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2012
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3325934/
https://ncbi.nlm.nih.gov/pubmed/22514734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0035353
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