Virally infected and matured human dendritic cells activate natural killer cells via cooperative activity of plasma membrane-bound TNF and IL-15

Recombinant adenovirus-engineered dendritic cells (Ad.DCs) are potent immunologic adjuvants of antiviral and anticancer vaccines. The effectiveness of Ad.DC-based vaccines may depend on the ability of Ad.DCs to crosstalk with natural killer (NK) cells and to activate, polarize, and bridge innate and...

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Autores principales: Vujanovic, Lazar, Szymkowski, David E., Alber, Sean, Watkins, Simon C., Vujanovic, Nikola L., Butterfield, Lisa H.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Hematology 2010
Materias:
Immunobiology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3324291/
https://ncbi.nlm.nih.gov/pubmed/20430958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-08-240325
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