Get5 Carboxyl-terminal Domain Is a Novel Dimerization Motif That Tethers an Extended Get4/Get5 Complex

Tail-anchored trans-membrane proteins are targeted to membranes post-translationally. The proteins Get4 and Get5 form an obligate complex that catalyzes the transfer of tail-anchored proteins destined to the endoplasmic reticulum from Sgt2 to the cytosolic targeting factor Get3. Get5 forms a homodim...

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Bibliographic Details
Main Authors: Chartron, Justin W., VanderVelde, David G., Rao, Meera, Clemons, William M.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2012
Subjects:
Protein Structure and Folding
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3318709/
https://ncbi.nlm.nih.gov/pubmed/22262836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.333252
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