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Soluble thrombomodulin reduces inflammation and prevents microalbuminuria induced by chronic endothelial activation in transgenic mice

Chronic kidney disease pathogenesis involves both tubular and vascular injuries. Despite abundant investigations to identify the risk factors, the involvement of chronic endothelial dysfunction in developing nephropathies is insufficiently explored. Previously, soluble thrombomodulin (sTM), a cofact...

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Main Authors: Rajashekhar, Gangaraju, Gupta, Akanksha, Marin, Abby, Friedrich, Jessica, Willuweit, Antje, Berg, David T., Cramer, Martin S., Sandusky, George E., Sutton, Timothy A., Basile, David P., Grinnell, Brian W., Clauss, Matthias
Format: Artigo
Jezik:Inglês
Izdano: American Physiological Society 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3311320/
https://ncbi.nlm.nih.gov/pubmed/22129968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00558.2011
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