Soluble thrombomodulin reduces inflammation and prevents microalbuminuria induced by chronic endothelial activation in transgenic mice

Chronic kidney disease pathogenesis involves both tubular and vascular injuries. Despite abundant investigations to identify the risk factors, the involvement of chronic endothelial dysfunction in developing nephropathies is insufficiently explored. Previously, soluble thrombomodulin (sTM), a cofact...

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Hauptverfasser: Rajashekhar, Gangaraju, Gupta, Akanksha, Marin, Abby, Friedrich, Jessica, Willuweit, Antje, Berg, David T., Cramer, Martin S., Sandusky, George E., Sutton, Timothy A., Basile, David P., Grinnell, Brian W., Clauss, Matthias
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2012
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3311320/
https://ncbi.nlm.nih.gov/pubmed/22129968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00558.2011
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