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Axonal transport deficits and degeneration can evolve independently in mouse models of amyotrophic lateral sclerosis
Axonal transport deficits have been reported in many neurodegenerative conditions and are widely assumed to be an immediate causative step of axon and synapse loss. By imaging changes in axonal morphology and organelle transport over time in several animal models of amyotrophic lateral sclerosis (AL...
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Hauptverfasser: | , , , , , |
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Format: | Artigo |
Sprache: | Inglês |
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National Academy of Sciences
2012
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Schlagworte: | |
Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3306689/ https://ncbi.nlm.nih.gov/pubmed/22371592 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1200658109 |
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