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Targeting Costimulatory Molecules to Improve Antitumor Immunity

The full activation of T cells necessitates the concomitant activation of two signals, the engagement of T-cell receptor by peptide/major histocompatibility complex II and an additional signal delivered by costimulatory molecules. The best characterized costimulatory molecules belong to B7/CD28 and...

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Main Authors: Capece, Daria, Verzella, Daniela, Fischietti, Mariafausta, Zazzeroni, Francesca, Alesse, Edoardo
格式: Artigo
語言:Inglês
出版: Hindawi Publishing Corporation 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3303883/
https://ncbi.nlm.nih.gov/pubmed/22500111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/926321
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