Gravar-mail: Very high volume haemofiltration (VHVHF) (8.75 l/hour) sustained during a 4 hour period of time can remove by filtration significantly higher amounts of cytokine compared with low volume haemofiltration (LVHF) (1 l/hour) and is accompanied by a significant drop in cytokines only in haemodynamical responders and survivors during early severe septic shock