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Genetic and Clinical Determinants of Early, Acute Calcineurin Inhibitor-Related Nephrotoxicity: Results from a Kidney Transplant Consortium

BACKGROUND: Calcineurin inhibitor (CNI)-related acute nephrotoxicity is a common complication of transplantation. Clinical factors and elevated CNI levels are associated with nephrotoxicity; however, they do not completely explain the risk. Genetics factors may also predispose individuals to nephrot...

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Détails bibliographiques
Auteurs principaux: Jacobson, Pamala A., Schladt, David, Israni, Ajay, Oetting, William S., Lin, Yi Cheng, Leduc, Robert, Guan, Weihau, Lamba, Vishal, Matas, Arthur J.
Format: Artigo
Langue:Inglês
Publié: 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3299910/
https://ncbi.nlm.nih.gov/pubmed/22334041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TP.0b013e3182461288
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