Recombinant Expression and Characterization of Human and Murine ACE2: Species-Specific Activation of the Alternative Renin-Angiotensin-System

Angiotensin-converting enzyme 2 (ACE2) is a monocarboxypeptidase of the renin-angiotensin-system (RAS) which is known to cleave several substrates among vasoactive peptides. Its preferred substrate is Angiotensin II, which is tightly involved in the regulation of important physiological functions in...

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Main Authors: Poglitsch, Marko, Domenig, Oliver, Schwager, Cornelia, Stranner, Stefan, Peball, Bernhard, Janzek, Evelyne, Wagner, Bettina, Jungwirth, Helmut, Loibner, Hans, Schuster, Manfred
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi Publishing Corporation 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3299299/
https://ncbi.nlm.nih.gov/pubmed/22518284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/428950
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