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AIDing the pursuit of IgA diversity

Direct evaluation of the contribution of somatic hypermutation (SHM) to mucosal immunity has been hampered by the lack of models able to dissociate SHM from class-switch recombination, which are both dependent on the cytidine deaminase AID. A new mouse AID model now demonstrates the critical role of...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Chen, Kang, Cerutti, Andrea
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2011
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3299005/
https://ncbi.nlm.nih.gov/pubmed/21321590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni0311-197
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