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Additive effect of TAp63 deficiency on the adrenocortical dysplasia (acd) phenotype

Adrenocortical dysplasia (acd) is a spontaneous autosomal recessive mouse mutation exhibiting caudal truncation, vertebral segmentation defects, hydronephrosis, limb hypoplasia, and perinatal lethality. Acd encodes TPP1, a component of the shelterin complex that maintains telomere integrity, and con...

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Autors principals: O’Connor, Bridget C., Macke, Erica L., Keegan, Catherine E.
Format: Artigo
Idioma:Inglês
Publicat: 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3298752/
https://ncbi.nlm.nih.gov/pubmed/22038471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00335-011-9360-4
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