Involvement of PPAR-γ in the neuroprotective and anti-inflammatory effects of angiotensin type 1 receptor inhibition: effects of the receptor antagonist telmisartan and receptor deletion in a mouse MPTP model of Parkinson's disease

BACKGROUND: Several recent studies have shown that angiotensin type 1 receptor (AT1) antagonists such as candesartan inhibit the microglial inflammatory response and dopaminergic cell loss in animal models of Parkinson's disease. However, the mechanisms involved in the neuroprotective and anti-...

Full description

Saved in:
Bibliographic Details
Main Authors: Garrido-Gil, Pablo, Joglar, Belen, Rodriguez-Perez, Ana I, Guerra, Maria J, Labandeira-Garcia, Jose L
Format: Artigo
Language:Inglês
Published: BioMed Central 2012
Subjects:
Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3298706/
https://ncbi.nlm.nih.gov/pubmed/22356806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-9-38
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items