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Retinoic acid modulates rat Ito cell proliferation, collagen, and transforming growth factor beta production.

Recent studies suggest that vitamin A plays an inhibitory role with respect to "activation" of the hepatic Ito cell, a likely effector of hepatic fibrogenesis. Ito cell "activation" during fibrogenesis is characterized by a decrease in intracellular vitamin A and an increase in c...

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Bibliographic Details
Main Authors: Davis, B H, Kramer, R T, Davidson, N O
Format: Artigo
Language:Inglês
Published: 1990
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC329845/
https://ncbi.nlm.nih.gov/pubmed/2254460
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