Tcf7 Is an Important Regulator of the Switch of Self-Renewal and Differentiation in a Multipotential Hematopoietic Cell Line

A critical problem in biology is understanding how cells choose between self-renewal and differentiation. To generate a comprehensive view of the mechanisms controlling early hematopoietic precursor self-renewal and differentiation, we used systems-based approaches and murine EML multipotential hema...

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Main Authors: Wu, Jia Qian, Seay, Montrell, Schulz, Vincent P., Hariharan, Manoj, Tuck, David, Lian, Jin, Du, Jiang, Shi, Minyi, Ye, Zhijia, Gerstein, Mark, Snyder, Michael P., Weissman, Sherman
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2012
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Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3297581/
https://ncbi.nlm.nih.gov/pubmed/22412390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002565
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