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IDENTIFICATION OF A NOVEL CLASS OF ANTI-INFLAMMATORY COMPOUNDS WITH ANTI-TUMOR ACTIVITY IN COLORECTAL AND LUNG CANCERS

Chronic inflammation is associated with 25% of all cancers. In the inflammation-cancer axis, prostaglandin E(2) (PGE(2)) is one of the major players. PGE(2) synthases (PGES) are the enzymes downstream of the cyclooxygenases (COXs) in the PGE(2) biosynthesis pathway. Microsomal prostaglandin E(2) syn...

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Hlavní autoři: Chang, Hui-Hua, Song, Zuohe, Wisner, Lee, Tripp, Tina, Gokhale, Vijay, Meuillet, Emmanuelle J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3295912/
https://ncbi.nlm.nih.gov/pubmed/21931968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10637-011-9748-8
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