PPARγ contributes to PKM2 and HK2 expression in fatty liver

Rapidly proliferating cells promote glycolysis in aerobic conditions, to increase growth rate. Expression of specific glycolytic enzymes, namely pyruvate kinase M2 and hexokinase 2, concurs to this metabolic adaptation, as their kinetics and intracellular localization favour biosynthetic processes r...

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Detalhes bibliográficos
Main Authors: Panasyuk, Ganna, Espeillac, Catherine, Chauvin, Céline, Pradelli, Ludivine A., Horie, Yasuo, Suzuki, Akira, Annicotte, Jean-Sebastien, Fajas, Lluis, Foretz, Marc, Verdeguer, Francisco, Pontoglio, Marco, Ferré, Pascal, Scoazec, Jean-Yves, Birnbaum, Morris J., Ricci, Jean-Ehrland, Pende, Mario
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Pub. Group 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3293420/
https://ncbi.nlm.nih.gov/pubmed/22334075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms1667
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