In Vitro Phenotypic, Genomic and Proteomic Characterization of a Cytokine-Resistant Murine β-TC3 Cell Line

Type 1 diabetes mellitus (T1DM) is caused by the selective destruction of insulin-producing β-cells. This process is mediated by cells of the immune system through release of nitric oxide, free radicals and pro-inflammatory cytokines, which induce a complex network of intracellular signalling cascad...

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Main Authors: Coppola, Antonina, Tomasello, Laura, Pizzolanti, Giuseppe, Pucci-Minafra, Ida, Albanese, Nadia, Di Cara, Gianluca, Cancemi, Patrizia, Pitrone, Maria, Bommarito, Alessandra, Carissimi, Elvira, Zito, Giovanni, Criscimanna, Angela, Galluzzo, Aldo, Giordano, Carla
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2012
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3290556/
https://ncbi.nlm.nih.gov/pubmed/22393382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0032109
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