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Tacrine-6-Ferulic Acid, a Novel Multifunctional Dimer, Inhibits Amyloid-β-Mediated Alzheimer's Disease-Associated Pathogenesis In Vitro and In Vivo

We have previously synthesized a series of hybrid compounds by linking ferulic acid to tacrine as multifunctional agents based on the hypotheses that Alzheimer's disease (AD) generates cholinergic deficiency and oxidative stress. Interestingly, we found that they may have potential pharmacologi...

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Detaylı Bibliyografya
Asıl Yazarlar: Pi, Rongbiao, Mao, Xuexuan, Chao, Xiaojuan, Cheng, Zhiyi, Liu, Mengfei, Duan, Xiaolu, Ye, Mingzhong, Chen, Xiaohong, Mei, Zhengrong, Liu, Peiqing, Li, Wenming, Han, Yifan
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2012
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3285653/
https://ncbi.nlm.nih.gov/pubmed/22384101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0031921
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