Tacrine-6-Ferulic Acid, a Novel Multifunctional Dimer, Inhibits Amyloid-β-Mediated Alzheimer's Disease-Associated Pathogenesis In Vitro and In Vivo

We have previously synthesized a series of hybrid compounds by linking ferulic acid to tacrine as multifunctional agents based on the hypotheses that Alzheimer's disease (AD) generates cholinergic deficiency and oxidative stress. Interestingly, we found that they may have potential pharmacologi...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Pi, Rongbiao, Mao, Xuexuan, Chao, Xiaojuan, Cheng, Zhiyi, Liu, Mengfei, Duan, Xiaolu, Ye, Mingzhong, Chen, Xiaohong, Mei, Zhengrong, Liu, Peiqing, Li, Wenming, Han, Yifan
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2012
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3285653/
https://ncbi.nlm.nih.gov/pubmed/22384101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0031921
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki