Tacrine-6-Ferulic Acid, a Novel Multifunctional Dimer, Inhibits Amyloid-β-Mediated Alzheimer's Disease-Associated Pathogenesis In Vitro and In Vivo

We have previously synthesized a series of hybrid compounds by linking ferulic acid to tacrine as multifunctional agents based on the hypotheses that Alzheimer's disease (AD) generates cholinergic deficiency and oxidative stress. Interestingly, we found that they may have potential pharmacologi...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Pi, Rongbiao, Mao, Xuexuan, Chao, Xiaojuan, Cheng, Zhiyi, Liu, Mengfei, Duan, Xiaolu, Ye, Mingzhong, Chen, Xiaohong, Mei, Zhengrong, Liu, Peiqing, Li, Wenming, Han, Yifan
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2012
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3285653/
https://ncbi.nlm.nih.gov/pubmed/22384101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0031921
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