Combined Use of a Solid-Phase Hexapeptide Ligand Library with Liquid Chromatography and Two-Dimensional Difference Gel Electrophoresis for Intact Plasma Proteomics

The intact plasma proteome is of great interest in biomarker studies because intact proteins reflect posttranslational protein processing such as phosphorylation that may correspond to disease status. We examined the utility of a solid-phase hexapeptide ligand library in combination with conventiona...

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Autors principals: Hagiwara, Tatsuo, Saito, Yumi, Nakamura, Yukiko, Tomonaga, Takeshi, Murakami, Yasufumi, Kondo, Tadashi
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2011
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3282153/
https://ncbi.nlm.nih.gov/pubmed/22389768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2011/739615
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