Targeted Expression of Cre Recombinase Provokes Placental-Specific DNA Recombination in Transgenic Mice

BACKGROUND: Inadequate placental development is associated with a high incidence of early embryonic lethality and serious pregnancy disorders in both humans and mice. However, the lack of well-defined trophoblast-specific gene regulatory elements has hampered investigations regarding the role of spe...

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Main Authors: Zhou, Cissy Chenyi, Chang, Jiang, Mi, Tiejuan, Abbasi, Shahrzad, Gu, Dongmin, Huang, Le, Zhang, WenZheng, Kellems, Rodney E., Schwartz, Robert J., Xia, Yang
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3281813/
https://ncbi.nlm.nih.gov/pubmed/22363401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0029236
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