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Extra-Thymic Physiological T Lineage Progenitor Activity Is Exclusively Confined to Cells Expressing either CD127, CD90, or High Levels of CD117

T cell development depends on continuous recruitment of progenitors from bone marrow (BM) to the thymus via peripheral blood. However, both phenotype and functional characteristics of physiological T cell precursors remain ill-defined. Here, we characterized a putative CD135(+)CD27(+) T cell progeni...

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Bibliografiske detaljer
Main Authors: Saran, Namita, Pommerencke, Jens, Witzlau, Katrin, Regelin, Malte, Krueger, Andreas
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3280270/
https://ncbi.nlm.nih.gov/pubmed/22355330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0030864
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