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New ionic derivatives of betulinic acid as highly potent anti-cancer agents

Betulinic acid is a natural compound with high in vitro cytotoxicity toward many cancer cells. However, the poor water solubility of this compound hampers an effective in vivo cancer study. We prepared new ionic derivatives of betulinic acid with higher water solubilities, without losing the structu...

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Autors principals: Challa, Suresh, Zhao, Hua, Gumbs, Angelique, Chetty, Chellu S., Bose, Himangshu S.
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3274637/
https://ncbi.nlm.nih.gov/pubmed/22264477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2011.12.102
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