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Crystallization of oligonucleotides containing A-­rich repeats suggests a structural contribution to the autoregulation mechanism of PABP translation

Eukaryotic poly(A)-binding protein (PABP) commonly binds to the 3′-UTR poly(A) tail of every mRNA, but it also binds to the 5′-UTR of PABP mRNA for autoregulation of its expression. In the sequence of the latter binding site, the contiguous A residues are segmented discretely by the insertion of sho...

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Autors principals: Kikuchi, Keita, Shimizu, Satoru, Sato, Yoshiteru, Morishita, Ella Czarina, Takénaka, Akio
Format: Artigo
Idioma:Inglês
Publicat: International Union of Crystallography 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3274399/
https://ncbi.nlm.nih.gov/pubmed/22297995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309111052110
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