Human Endogenous Retrovirus K(HML-2) Gag- and Env-Specific T-Cell Responses Are Infrequently Detected in HIV-1-Infected Subjects Using Standard Peptide Matrix-Based Screening

T-cell responses to human endogenous retrovirus (HERV) K(HML-2) Gag and Env were mapped in HIV-1-infected subjects using 15mer peptides. Small peptide pools and high concentrations were used to maximize sensitivity. In the 23 subjects studied, only three bona fide HERV-K(HML-2)-specific responses we...

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Autori principali: Jones, R. Brad, John, Vivek M., Hunter, Diana V., Martin, Eric, Mujib, Shariq, Mihajlovic, Vesna, Burgers, Peter C., Luider, Theo M., Gyenes, Gabor, Sheppard, Neil C., SenGupta, Devi, Tandon, Ravi, Yue, Feng-Yun, Benko, Erika, Kovacs, Colin, Nixon, Douglas F., Ostrowski, Mario A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2012
Soggetti:
Clinical Immunology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3272926/
https://ncbi.nlm.nih.gov/pubmed/22205657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.05583-11
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