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A Concise Total Synthesis of (±)- and (−)-Okilactomycin D

[Image: see text] The spirotetronate okilactomycin D (7) has been efficiently synthesized by a route featuring a substrate-controlled, diastereoselective (8:1) intramolecular Diels-Alder (IMDA) reaction of 11. The assigned absolute configuration of (−)-7 was confirmed.

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Detalhes bibliográficos
Main Authors: Niu, Dawen, Hoye, Thomas R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3272355/
https://ncbi.nlm.nih.gov/pubmed/22273402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol203355g
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