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Tryptase activates isolated adult cardiac fibroblasts via protease activated receptor-2 (PAR-2)

Protease activated receptor-2 (PAR-2) derived cycloxygenase-2 (COX-2) was recently implicated in a cardiac mast cell and fibroblast cross-talk signaling cascade mediating myocardial remodeling secondary to mechanical stress. We designed this study to investigate in vitro assays of isolated adult car...

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Détails bibliographiques
Auteurs principaux: Murray, David B., McLarty-Williams, Jennifer, Nagalla, Krishna T., Janicki, Joseph S.
Format: Artigo
Langue:Inglês
Publié: Springer Netherlands 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3271199/
https://ncbi.nlm.nih.gov/pubmed/21786087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12079-011-0146-y
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