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Frizzled7 as an emerging target for cancer therapy
Wnt proteins are secreted glycoproteins that bind to the N-terminal extra-cellular cysteine-rich domain of the Frizzled (Fzd) receptor family. The Fzd receptors can respond to Wnt proteins in the presence of Wnt co-receptors to activate the canonical and non-canonical Wnt pathways. Recent studies in...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3268941/ https://ncbi.nlm.nih.gov/pubmed/22182510 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2011.12.009 |
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