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Evaluation of a Cell Penetrating Prenylated Peptide Lacking an Intrinsic Fluorophore via in situ Click Reaction

Protein prenylation involves the addition of either a farnesyl (C(15)) or geranylgeranyl (C(20)) isoprenoid moiety onto the C-terminus of many proteins. This natural modification serves to direct a protein to the plasma membrane of the cell. A recently discovered application of prenylated peptides i...

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Detalhes bibliográficos
Main Authors: Ochocki, Joshua D., Mullen, Daniel G., Wattenberg, Elizabeth V., Distefano, Mark D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3266054/
https://ncbi.nlm.nih.gov/pubmed/21632248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2011.04.138
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