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Human DNA polymerase η is pre-aligned for dNTP binding and catalysis
Pre-steady state kinetic studies on Y-family DNA polymerase η (Polη) have suggested that the polymerase undergoes a rate-limiting conformational change step before the phosphoryl transfer of the incoming nucleotide to the primer terminus. However, the nature of this rate-limiting conformational chan...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3265613/ https://ncbi.nlm.nih.gov/pubmed/22154937 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2011.11.038 |
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