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Association of the GGCX (CAA)16/17 repeat polymorphism with higher warfarin dose requirements in African Americans

OBJECTIVE: Little is known about genetic contributors to higher than usual warfarin dose requirements, particularly for African Americans. This study tested the hypothesis that the γ-glutamyl carboxylase (GGCX) genotype contributes to warfarin dose requirements >7.5 mg/day in an African American...

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Detalhes bibliográficos
Main Authors: Cavallari, Larisa H., Perera, Minoli, Wadelius, Mia, Deloukas, Panos, Taube, Gelson, Patel, Shitalben R., Aquino-Michaels, Keston, Viana, Marlos A.G., Shapiro, Nancy L., Nutescu, Edith A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3261355/
https://ncbi.nlm.nih.gov/pubmed/22158446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FPC.0b013e32834f288f
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