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On the statistical properties of family-based association tests in datasets containing both pedigrees and unrelated case–control samples
A common approach to genetic mapping of loci for complex diseases is to perform a genome-wide association study (GWAS) by analyzing a vast number of SNP markers in cohorts of unrelated cases and controls. A direct motivation for the case–control design is that unrelated, affected individuals can be...
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| Hlavní autoři: | , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Nature Publishing Group
2012
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3260916/ https://ncbi.nlm.nih.gov/pubmed/21934707 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2011.173 |
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